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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
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規(guī)格

庫存

目錄價

會員專享價

數(shù)量

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基本信息

英文名稱	Adezmapimod Hydrochloride \| SB 203580 Hydrochloride \| RWJ 64809 Hydrochloride
中文名稱	Adezmapimod Hydrochloride \| SB 203580 Hydrochloride \| RWJ 64809 Hydrochloride
CAS號	869185-85-3
分子式	C21H17ClFN3OS
分子量	413.90
外觀	Light yellow to yellow powder
儲存條件	4°C, sealed storage, away from moisture

產(chǎn)品詳情

Adezmapimod (SB 203580; RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC₅₀s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3β and PKBα with IC₅₀s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator.