英文名稱 | Carboplatin |
---|---|
中文名稱 | 卡鉑 |
CAS號 | 41575-94-4 |
分子式 | C6H12N2O4Pt |
分子量 | 371.25 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Carboplatin |
---|---|
中文名稱 | 卡鉑 |
CAS號 | 41575-94-4 |
分子式 | C6H12N2O4Pt |
分子量 | 371.25 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.