英文名稱 | SX 011/SX-011 |
---|---|
中文名稱 | SX 011/SX-011 |
CAS號(hào) | 309913-42-6 |
分子式 | C26H27ClFN3O3 |
分子量 | 483.96 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | SX 011/SX-011 |
---|---|
中文名稱 | SX 011/SX-011 |
CAS號(hào) | 309913-42-6 |
分子式 | C26H27ClFN3O3 |
分子量 | 483.96 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
SX-011 is a p38 inhibitor with IC50 values for p38 and p38β of 9 nM and 90 nM, respectively. Additionally, SX-011 blocks JNK-2 with an IC50 of 100 nM. Orally, SX-011 is bioavailable.