奧拉替尼馬來酸鹽 (1208319-27-0)

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Oclacitinib Maleate (PF-03394197 Maleate)

產品編號：CL2531 CAS No.：1640292-55-2 MDLNo： 分子式：C19H27N5O6S 分子量：453.51

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規(guī)格	庫存	目錄價	會員專享價	數量
5 mg	3-5days	￥650.00	登錄后可見	- +
10 mg	3-5days	￥975.00	登錄后可見	- +
25 mg	3-5days	￥1800.00	登錄后可見	- +

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基本信息
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基本信息

英文名稱	Oclacitinib Maleate (PF-03394197 Maleate)
中文名稱	奧拉替尼馬來酸鹽 (1208319-27-0)
CAS號	1640292-55-2
分子式	C19H27N5O6S
分子量	453.51
外觀	White to off-white powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產品詳情

Oclacitinib maleate (formerly PF-03394197 maleate) is a novel and potent inhibitor of JAK (Janus kinase) family members with IC50 values ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM. Oclacitinib did not inhibit a panel of 38 non-JAK kinases and is the most potent at inhibiting JAK1. Oclacitinib also inhibits the function of JAK1-dependent cytokines involved in allergy and inflammation as well as pruritus. Cclacitinib is a targeted therapy that selectively inhibits JAK1-dependent cytokines involved in allergy, inflammation, and pruritus and suggests these are the mechanisms by which oclacitinib effectively controls clinical signs associated with allergic skin disease in dogs.

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CL2531

奧拉替尼馬來酸鹽 (1208319-27-0)

1640292-55-2 98+% 3-5days

￥650.00 5 mg