英文名稱 | SL 327 |
---|---|
中文名稱 | SL 327 |
CAS號 | 305350-87-2 |
分子式 | C16H12F3N3S |
分子量 | 335.35 |
外觀 | White to off-white powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
規(guī)格 | 庫存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 | |
---|---|---|---|---|---|
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英文名稱 | SL 327 |
---|---|
中文名稱 | SL 327 |
CAS號 | 305350-87-2 |
分子式 | C16H12F3N3S |
分子量 | 335.35 |
外觀 | White to off-white powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII; capable of transport through the blood-brain barrier.
PMID: 10969080 DOI: 10.1074/jbc.M006168200
Current Development Status of MEK Inhibitors.
PMID: 28954413 PMCID: PMC6151813 DOI: 10.3390/molecules22101551
A necessity for MAP kinase activation in mammalian spatial learning
PMID: 10541468 PMCID: PMC311312 DOI: 10.1101/lm.6.5.478